Dick Dastardly and Muttley - I've never been a big fan of anything Hannah Barbera, but you have to give it up for these guys. Two of the best voices in cartoon history and their chemistry was pretty good too!
Droopy Dog. I always thought Droopy and actor, Leo G. Carrol looked alike. Carrol was the boss of U.N.C.L.E. agents, Napoleon Solo (Robert Vaughn) and Illya Kuriakin (David McCallum,,,who now plays "Ducky" on NCIS). The show was called "The Man From U.N.C.L.E."